Functional Characterization of Small Alarmone Synthetase and Small Alarmone Hydrolase Proteins from Treponema denticola-Reference-Cited by-同舟云学术

Functional Characterization of Small Alarmone Synthetase and Small Alarmone Hydrolase Proteins from Treponema denticola

Published:2023-08-17 Issue:4 Volume:11 Page:
ISSN:2165-0497
Container-title:Microbiology Spectrum
language:en
Short-container-title:Microbiol Spectr

Author:

Wang Miao¹,Tang Nga-Yeung²³,Xie Shujie¹,Watt Rory M.¹^ORCID

Affiliation:

1. Faculty of Dentistry, The University of Hong Kong, Pok Fu Lam, Hong Kong SAR, China

2. Department of Pathology and Laboratory Medicine, Beaumont Health, Royal Oak, Michigan, USA

3. Department of Pathology and Laboratory Medicine, Oakland University William Beaumont School of Medicine, Auburn Hills, Michigan, USA

Abstract

The spirochete bacterium Treponema denticola is a common component of the oral microbiota. However, it may play important pathological roles in multispecies oral infectious diseases such as periodontitis: a severe and destructive form of gum disease, which is a major cause of tooth loss in adults.

Funder

Research Grants Council, University Grants Committee

University of Hong Kong

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Link

https://journals.asm.org/doi/pdf/10.1128/spectrum.05100-22

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1. Breaking bad nucleotides: understanding the regulatory mechanisms of bacterial small alarmone hydrolases;Trends in Microbiology;2024-08

2. Characterization of c‐di‐AMP signaling in the periodontal pathobiont, Treponema denticola;Molecular Oral Microbiology;2024-03-04