Transferrin Receptor Protein 1 Cooperates with mGluR2 To Mediate the Internalization of Rabies Virus and SARS-CoV-2-Reference-Cited by-同舟云学术

Transferrin Receptor Protein 1 Cooperates with mGluR2 To Mediate the Internalization of Rabies Virus and SARS-CoV-2

Published:2023-02-28 Issue:2 Volume:97 Page:
ISSN:0022-538X
Container-title:Journal of Virology
language:en
Short-container-title:J Virol

Author:

Wang Xinxin¹,Wen Zhiyuan¹,Cao Huizhen¹,Luo Jie¹,Shuai Lei¹,Wang Chong¹,Ge Jinying¹,Wang Xijun¹,Bu Zhigao¹^ORCID,Wang Jinliang¹^ORCID

Affiliation:

1. State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, People’s Republic of China

Abstract

We previously found that metabotropic glutamate receptor subtype 2 (mGluR2) is an entry receptor for RABV in vitro , and an important internalization factor for SARS-CoV-2 in vitro and in vivo . However, whether mGluR2 is required for RABV infection in vivo was unknown.

Funder

National Natural Science Foundation of China

MOST | National Key Research and Development Program of China

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/jvi.01611-22

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