Emergence in Klebsiella pneumoniae and Enterobacter cloacae Clinical Isolates of the VIM-4 Metallo-β-Lactamase Encoded by a Conjugative Plasmid-Reference-Cited by-同舟云学术

Emergence in Klebsiella pneumoniae and Enterobacter cloacae Clinical Isolates of the VIM-4 Metallo-β-Lactamase Encoded by a Conjugative Plasmid

Published:2004-02 Issue:2 Volume:48 Page:648-650
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Luzzaro Francesco¹,Docquier Jean-Denis²,Colinon Céline²,Endimiani Andrea¹,Lombardi Gianluigi¹,Amicosante Gianfranco³,Rossolini Gian Maria²,Toniolo Antonio¹

Affiliation:

1. Laboratorio di Microbiologia, Ospedale di Circolo, and Università dell'Insubria, I-21100 Varese

2. Dipartimento di Biologia Molecolare, Sezione di Microbiologia, Università di Siena, I-53100 Siena

3. Dipartimento di Scienze e Tecnologie Biomediche, Università di L'Aquila, I-67100 L'Aquila, Italy

Abstract

ABSTRACT Resistance to carbapenems is an emerging problem among gram-negative hospital pathogens. A transferable plasmid encoding the VIM-4 metallo-β-lactamase was detected in isolates of Klebsiella pneumoniae and Enterobacter cloacae obtained from a single patient under carbapenem therapy. Thus, enterobacteria appear to increasingly contribute to the spread of VIM-type enzymes.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.48.2.648-650.2004

Reference20 articles.

1. Bush, K. 2001. New β-lactamases in gram-negative bacteria: diversity and impact on the selection of antimicrobial therapy. Clin. Infect. Dis.32:1085-1089.

2. Docquier, J.-D., F. Luzzaro, G. Amicosante, A. Toniolo, and G. M. Rossolini. 2001. Multidrug-resistant Pseudomonas aeruginosa producing PER-1 extended-spectrum serine-β-lactamase and VIM-2 metallo-β-lactamase. Emerg. Infect. Dis.7:910-911.

3. VIM-1 Metallo-β-Lactamase-Producing Klebsiella pneumoniae Strains in Greek Hospitals

4. Jarlier, V., M.-H. Nicholas, G. Fournier, and A. Philippon. 1988. Extended broad-spectrum β-lactamases conferring transferable resistance to newer β-lactam agents in Enterobacteriaceae: hospital prevalence and susceptibility patterns. Rev. Infect. Dis.10:867-878.

5. Cloning and Characterization of bla VIM , a New Integron-Borne Metallo-β-Lactamase Gene from a Pseudomonas aeruginosa Clinical Isolate

Cited by 93 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. 1,2,4‐Triazole‐3‐Thione Analogues with a 2‐Ethylbenzoic Acid at Position 4 as VIM‐type Metallo‐β‐Lactamase Inhibitors;ChemMedChem;2022-02-04

2. Trends of major antimicrobial resistance phenotypes in enterobacterales and gram-negative non-fermenters from ATLAS and EARS-net surveillance systems: Italian vs. European and global data, 2008-2018;Diagnostic Microbiology and Infectious Disease;2021-12

3. 1,2,4-Triazole-3-thione compounds with a 4-ethyl alkyl/aryl sulfide substituent are broad-spectrum metallo-β-lactamase inhibitors with re-sensitization activity;European Journal of Medicinal Chemistry;2021-12

4. 4-Alkyl-1,2,4-triazole-3-thione analogues as metallo-β-lactamase inhibitors;Bioorganic Chemistry;2021-08

5. Metallo-β-Lactamases: Structure, Function, Epidemiology, Treatment Options, and the Development Pipeline;Antimicrobial Agents and Chemotherapy;2020-09-21