Development of an Enzyme-Linked Immunosorbent Assay for Rapid Detection of Dengue Virus (DENV) NS1 and Differentiation of DENV Serotypes during Early Infection

Author:

Lai Szu-Chia1,Huang Yu-Yine1,Shu Pei-Yun2,Chang Shu-Fen2,Hsieh Po-Shiuan1,Wey Jiunn-Jye1,Tsai Meng-Hung1,Ben Ren-Jy3,Hsu Yi-Ming3,Fang Yi-Chien4,Hsiao Mei-Ling5,Lin Chang-Chi1

Affiliation:

1. Institute of Preventive Medicine, National Defense Medical Center, Taipei City, Taiwan

2. Taiwan Centers for Disease Control, Taipei City, Taiwan

3. Kaohsiung Armed Forces General Hospital, Kaohsiung City, Taiwan

4. Zuoying Branch of Kaohsiung Armed Forces General Hospital, Kaohsiung City, Taiwan

5. Tangshan Branch of Kaohsiung Armed Forces General Hospital, Kaohsiung City, Taiwan

Abstract

Dengue fever, caused by infections with the dengue virus (DENV), affects nearly 400 million people globally every year. Early diagnosis and management can reduce the morbidity and mortality rates of severe forms of dengue disease as well as decrease the risk of wider outbreaks.

Funder

Institute of Preventive Medicine

National Health Research Institutes

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

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