Igniting the slow burn of post-COVID conditions

Author:

Henderson Jeffrey P.12ORCID

Affiliation:

1. Department of Medicine, Division of Infectious Diseases, Washington University School of Medicine , St. Louis, Missouri, USA

2. Center for Women’s Infectious Disease Research, Washington University School of Medicine , St. Louis, Missouri, USA

Abstract

ABSTRACT Post-COVID conditions (PCCs) are persistent new patient symptoms occurring after acute COVID-19 infection and are an increasingly appreciated dimension of the COVID-19 pandemic. The factors that cause PCCs are not well understood. In recent work, Gebo et al. identify a connection between acute IL-6 levels, early COVID-19 convalescent plasma (CP) administration, and later PCCs in subjects from a randomized controlled trial of acutely ill subjects enrolled in 2020 to 2021 (K. A. Gebo, S. L. Heath, Y. Fukuta, X. Zhu, et al., mBio e00618-23, 2023, https://doi.org/10.1128/mbio.00618-23 ). These results may be viewed as part of an emerging picture linking the intensity of inflammatory responses during acute infection to later PCCs.

Funder

HHS | National Institutes of Health

Longer Life Foundation

Publisher

American Society for Microbiology

Subject

Virology,Microbiology

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