Spread of OXA-48-Encoding Plasmid in Turkey and Beyond-Reference-Cited by-同舟云学术

Spread of OXA-48-Encoding Plasmid in Turkey and Beyond

Published:2010-03 Issue:3 Volume:54 Page:1369-1373
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Carrër Amélie¹,Poirel Laurent¹,Yilmaz Mesut²,Akan Özay Arikan³,Feriha Cilli⁴,Cuzon Gaëlle¹,Matar Ghassan⁵,Honderlick Patrick⁶,Nordmann Patrice¹

Affiliation:

1. Service de Bactériologie-Virologie, INSERM U914 Emerging Resistance to Antibiotics, Hôpital de Bicêtre, Assistance Publique/Hôpitaux de Paris, Faculté de Médecine Paris Sud, K.-Bicêtre, France

2. Infectious Diseases and Clinical Microbiology Department, Cerrahpasa Medical Faculty, University of Istanbul, Istanbul, Turkey

3. Central Laboratories, Medical School, Ankara University, Ibni Sina Hospital, Ankara, Turkey

4. Ege University Medical Faculty, Department of Microbiology and Clinical Microbiology, Izmir, Turkey

5. American University of Beirut, Beirut, Lebanon

6. Service de Microbiologie, Hôpital Foch, Suresnes, France

Abstract

ABSTRACT Eighteen carbapenem-resistant, OXA-48-positive enterobacterial isolates recovered from Turkey, Lebanon, Egypt, France, and Belgium were analyzed. In most isolates, similar 70-kb plasmids carrying the carbapenemase gene bla OXA-48 were identified. That gene was located within either transposon Tn 1999 or transposon Tn 1999.2 , which was always inserted within the same gene. This work highlights the current plasmid-mediated dissemination of the OXA-48 carbapenemase worldwide.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.01312-09

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