CsrA Supports both Environmental Persistence and Host-Associated Growth of Acinetobacter baumannii

Author:

Farrow John M.1,Wells Greg1,Palethorpe Samantha1,Adams Mark D.2ORCID,Pesci Everett C.1ORCID

Affiliation:

1. Department of Microbiology and Immunology, The Brody School of Medicine at East Carolina University, Greenville, North Carolina, USA

2. The Jackson Laboratory for Genomic Medicine, Farmington, Connecticut, USA

Abstract

Acinetobacter baumannii is an opportunistic and frequently multidrug-resistant Gram-negative bacterial pathogen that primarily infects critically ill individuals. Indirect transmission from patient to patient in hospitals can drive infections, supported by this organism’s abilities to persist on dry surfaces and rapidly colonize susceptible individuals. To investigate how A. baumannii survives on surfaces, we cultured A. baumannii in liquid media for several days and then analyzed isolates that lost the ability to survive drying.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

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