In Vitro Activities of Anidulafungin and Other Antifungal Agents against Biofilms Formed by Clinical Isolates of Different Candida and Aspergillus Species-Reference-Cited by-同舟云学术

In Vitro Activities of Anidulafungin and Other Antifungal Agents against Biofilms Formed by Clinical Isolates of Different Candida and Aspergillus Species

Published:2011-06 Issue:6 Volume:55 Page:3031-3035
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Fiori Barbara¹,Posteraro Brunella¹,Torelli Riccardo¹,Tumbarello Mario²,Perlin David S.³,Fadda Giovanni¹,Sanguinetti Maurizio¹

Affiliation:

1. Institutes of Microbiology, Università Cattolica del Sacro Cuore, Largo F. Vito, 1, 00168 Rome, Italy

2. Infectious Diseases, Università Cattolica del Sacro Cuore, Largo F. Vito, 1, 00168 Rome, Italy

3. Public Health Research Institute, New Jersey Medical School, UMDNJ, Newark, New Jersey

Abstract

ABSTRACT We tested the activities of anidulafungin and other antifungal agents against clinical isolates of different fungal species. For Candida species, high sessile MIC 90 s (SMIC 90 s) were obtained for fluconazole, voriconazole, and amphotericin B, whereas the anidulafungin SMIC 90 s were very low, as were those for caspofungin. Comparatively, for Aspergillus species, higher SMIC 90 values were obtained not only for amphotericin B and voriconazole but also for the echinocandins.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.01569-10

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