Genetic Interaction Analysis Reveals that Cryptococcus neoformans Utilizes Multiple Acetyl-CoA-Generating Pathways during Infection-Reference-Cited by-同舟云学术

Genetic Interaction Analysis Reveals that Cryptococcus neoformans Utilizes Multiple Acetyl-CoA-Generating Pathways during Infection

Published:2022-08-30 Issue:4 Volume:13 Page:
ISSN:2150-7511
Container-title:mBio
language:en
Short-container-title:mBio

Author:

Alden Katy M.¹,Jezewski Andrew J.¹,Beattie Sarah R.¹,Fox David²³⁴,Krysan Damian J.¹⁵^ORCID

Affiliation:

1. Department of Pediatrics Carver College of Medicine, University of Iowa, Iowa City Iowa, USA

2. UCB Biosciences, Bainbridge Island, Washington, USA

3. Seattle Structural Genomics Center for Infectious Disease (SSGCID), Seattle, Washington, USA

4. Beryllium Discovery Corp., Bainbridge Island, Washington, USA

5. Microbiology/Immunology, Carver College of Medicine, University of Iowa, Iowa City Iowa, USA

Abstract

The adaptation of environmental fungal pathogens to the mammalian host is critical to pathogenesis. Of these adaptations, the remodeling of carbon metabolism is particularly important.

Funder

HHS | NIH | National Institute of Allergy and Infectious Diseases

Publisher

American Society for Microbiology

Subject

Virology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/mbio.01279-22

Reference32 articles.

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5. Genotypic Diversity Is Associated with Clinical Outcome and Phenotype in Cryptococcal Meningitis across Southern Africa

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