Improved Performance of a Rapid Immunochromatographic Assay for Detection of PBP2a in Non-Staphylococcus aureus Staphylococcal Species

Author:

Canver Matthew C.1,Gonzalez Mark D.2,Ford Bradley A.3,Arnold Amanda R.2,Lawhon Sara D.4ORCID,Burnham Carey-Ann D.5ORCID,Jenkins Stephen G.1,Burd Eileen M.6,Westblade Lars F.1

Affiliation:

1. Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, New York, USA

2. Children’s Healthcare of Atlanta, Atlanta, Georgia, USA

3. Department of Pathology, University of Iowa Carver College of Medicine, Iowa City, Iowa, USA

4. Texas A&M University College of Veterinary Medicine, College Station, Texas, USA

5. Department of Pathology and Immunology, Washington University School of Medicine in St. Louis, St. Louis, Missouri, USA

6. Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, Georgia, USA

Abstract

Non- Staphylococcus aureus staphylococcal species (non-SASS) are important pathogens in both animal and human populations. The development of β-lactam resistance in non-SASS through acquisition and expression of penicillin-binding protein 2a (PBP2a) represents a significant clinical and public health threat.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

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