Evolution of Antibody Responses in HIV-1 CRF01_AE Acute Infection: Founder Envelope V1V2 Impacts the Timing and Magnitude of Autologous Neutralizing Antibodies-Reference-Cited by-同舟云学术

Evolution of Antibody Responses in HIV-1 CRF01_AE Acute Infection: Founder Envelope V1V2 Impacts the Timing and Magnitude of Autologous Neutralizing Antibodies

Published:2023-02-28 Issue:2 Volume:97 Page:
ISSN:0022-538X
Container-title:Journal of Virology
language:en
Short-container-title:J Virol

Author:

Kuriakose Gift Syna¹²,Wieczorek Lindsay¹²,Sanders-Buell Eric¹²,Zemil Michelle¹²,Molnar Sebastian¹²,Donofrio Gina¹²,Townsley Samantha¹²,Chenine Agnes L.¹²,Bose Meera¹²,Trinh Hung V.¹²,Barrows Brittani M.¹²,Sriplienchan Somchai³,Kitsiripornchai Suchai³,Nitayapan Sorachai⁴,Eller Leigh-Anne¹²,Rao Mangala¹⁵,Ferrari Guido⁶⁷,Michael Nelson L.¹⁵,Ake Julie A.¹⁵,Krebs Shelly J.¹²,Robb Merlin L.¹²,Tovanabutra Sodsai¹²,Polonis Victoria R.¹⁵^ORCID

Affiliation:

1. U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA

2. Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, Maryland, USA

3. Department of Retrovirology, Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand

4. Royal Thai Army, Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand

5. Walter Reed Army Institute of Research, Silver Spring, Maryland, USA

6. Human Vaccine Institute, Duke University School of Medicine, Durham, North Carolina, USA

7. Department of Surgery, Duke University School of Medicine, Durham, North Carolina, USA

Abstract

Development of an effective HIV-1 vaccine will be facilitated by better understanding the dynamics between the founder virus and the early humoral responses. Variations between subtypes may influence the evolution of immune responses and should be considered as we strive to understand these dynamics.

Funder

U.S. Department of Defense

Swiss National Science Foundation

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/jvi.01635-22

Reference110 articles.

1. HIV subtype diversity worldwide

2. Co-evolution of a broadly neutralizing HIV-1 antibody and founder virus