The Leishmania donovani Ortholog of the Glycosylphosphatidylinositol Anchor Biosynthesis Cofactor PBN1 Is Essential for Host Infection-Reference-Cited by-同舟云学术

The Leishmania donovani Ortholog of the Glycosylphosphatidylinositol Anchor Biosynthesis Cofactor PBN1 Is Essential for Host Infection

Published:2022-06-28 Issue:3 Volume:13 Page:
ISSN:2150-7511
Container-title:mBio
language:en
Short-container-title:mBio

Author:

Roberts Adam¹²,Nagar Rupa³,Brandt Cordelia⁴,Harcourt Katherine⁴,Clare Simon⁴,Ferguson Michael A. J.³,Wright Gavin J.¹²^ORCID

Affiliation:

1. Cell Surface Signalling Laboratory, Wellcome Sanger Institute, Hinxton, Cambridge, United Kingdom

2. Department of Biology, Hull York Medical School, York Biomedical Research Institute, University of York, York, United Kingdom

3. Wellcome Centre for Anti-Infectives Research, School of Life Sciences, University of Dundee, Dundee, United Kingdom

4. Pathogen Support Team, Wellcome Sanger Institute, Hinxton, Cambridge, United Kingdom

Abstract

Visceral leishmaniasis is a deadly infectious disease caused by the parasitesLeishmania donovaniandLeishmania infantum. It remains a major global health problem, and there is no licensed highly effective vaccine.

Funder

Wellcome

Publisher

American Society for Microbiology

Subject

Virology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/mbio.00433-22

Reference70 articles.

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3. Review of the current treatments for leishmaniases

4. Laboratory confirmed miltefosine resistant cases of visceral leishmaniasis from India

5. Drug Resistance in Leishmaniasis

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