Molecular Characterization of the First Ebola Virus Isolated in Italy, from a Health Care Worker Repatriated from Sierra Leone

Author:

Castilletti Concetta1,Carletti Fabrizio1,Gruber Cesare E. M.1,Bordi Licia1,Lalle Eleonora1,Quartu Serena1,Meschi Silvia1,Lapa Daniele1,Colavita Francesca1,Chiappini Roberta1,Mazzarelli Antonio1,Marsella Patrizia1,Petrosillo Nicola1,Nicastri Emanuele1,Chillemi Giovanni2,Valentini Alessio34,Desideri Alessandro45,Di Caro Antonino1,Ippolito Giuseppe1,Capobianchi Maria R.1

Affiliation:

1. National Institute for Infectious Diseases L. Spallanzani, Rome, Italy

2. CINECA, Rome, Italy

3. Department for Innovation in Biological, Agro-food and Forest Systems (DIBAF), University of Tuscia, Viterbo, Italy

4. Molecular Digital Diagnostics (MDD), Viterbo, Italy

5. Department of Biology, University of Rome Tor Vergata, Rome, Italy

Abstract

ABSTRACT Here, we report the complete genome sequence of an Ebola virus (EBOV) isolated from a health worker repatriated from Sierra Leone to Italy in November 2014. The sequence, clustering in clade 3 of the Sierra Leone sequences, was analyzed with respect to mutations possibly affecting diagnostic and therapeutic targets as well as virulence.

Publisher

American Society for Microbiology

Subject

Genetics,Molecular Biology

Reference21 articles.

1. Animal models for Ebola and Marburg virus infections

2. Evaluation of Perceived Threat Differences Posed by Filovirus Variants

3. Burke J. 1978. Ebola haemorrhagic fever in Zaire 1976. Bull World Health Organ 56:271–293.

4. Emergence of Zaire Ebola Virus Disease in Guinea

5. WHO. 2015. Ebola situation report—6 May 2015. WHO Geneva Switzerland. http://apps.who.int/ebola/en/current-situation/ebola-situation-report-6-may-2015.

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