Persistence Alters the Interaction between Chlamydia trachomatis and Its Host Cell-Reference-Cited by-同舟云学术

Persistence Alters the Interaction between Chlamydia trachomatis and Its Host Cell

Published:2021-07-15 Issue:8 Volume:89 Page:
ISSN:0019-9567
Container-title:Infection and Immunity
language:en
Short-container-title:Infect Immun

Author:

Brockett Mary R.¹²,Liechti George W.¹^ORCID

Affiliation:

1. Department of Microbiology and Immunology, Uniformed Services University, Bethesda, Maryland, USA

2. Henry Jackson Foundation for the Advancement of Military Medicine, Bethesda, Maryland, USA

Abstract

In response to stress, the obligate intracellular pathogen Chlamydia trachomatis stops dividing and halts its biphasic developmental cycle. The infectious, extracellular form of this bacterium is highly susceptible to killing by the host immune response, and by pausing development, Chlamydia can survive in an intracellular, “aberrant” state for extended periods of time.

Funder

DOD | Uniformed Services University of the Health Sciences

HHS | NIH | National Institute of General Medical Sciences

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Link

https://journals.asm.org/doi/pdf/10.1128/IAI.00685-20

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