High Prevalence of Human Bocavirus Detected in Young Children with Severe Acute Lower Respiratory Tract Disease by Use of a Standard PCR Protocol and a Novel Real-Time PCR Protocol

Author:

Kleines Michael1,Scheithauer Simone1,Rackowitz Annette2,Ritter Klaus1,Häusler Martin3

Affiliation:

1. Division of Virology, Department of Medical Microbiology, University Hospital Aachen, RWTH Aachen, Pauwelsstrasse 30, 52074 Aachen, Germany

2. Department of Pediatric Cardiology, University Hospital Aachen, RWTH Aachen, Pauwelsstrasse 30, 52074 Aachen, Germany

3. Department of Pediatrics, University Hospital Aachen, RWTH Aachen, Pauwelsstrasse 30, 52074 Aachen, Germany

Abstract

ABSTRACT The human bocavirus (HBoV) was recently isolated from respiratory tract samples. Within a study collective of children with severe lower respiratory tract disease, the patients testing positive for HBoV (12.8%) had a higher rate of underlying cardiopulmonary disease. Viral loads in respiratory tract specimens varied from 10 2 to 10 10 genome equivalents/ml.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Cited by 62 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Prevalence of human bocavirus infections in Europe. A systematic review and meta‐analysis;Transboundary and Emerging Diseases;2021-07-22

2. Human bocavirus and human metapneumovirus in hospitalized children with lower respiratory tract illness in Changsha, China;Influenza and Other Respiratory Viruses;2018-01-11

3. The Role of the Human Bocavirus (HBoV) in Respiratory Infections;Advanced Techniques in Diagnostic Microbiology;2018

4. Bocavirus Viremia and Hepatitis in an Immunocompetent Child;Balkan Medical Journal;2017-05-26

5. Respiratory infections of the human bocavirus;The Microbiology of Respiratory System Infections;2016

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