The Papain-Like Protease of Porcine Reproductive and Respiratory Syndrome Virus Impedes STING Translocation from the Endoplasmic Reticulum to the Golgi Apparatus by Deubiquitinating STIM1-Reference-Cited by-同舟云学术

The Papain-Like Protease of Porcine Reproductive and Respiratory Syndrome Virus Impedes STING Translocation from the Endoplasmic Reticulum to the Golgi Apparatus by Deubiquitinating STIM1

Published:2023-04-27 Issue:4 Volume:97 Page:
ISSN:0022-538X
Container-title:Journal of Virology
language:en
Short-container-title:J Virol

Author:

Diao Feifei¹,Bai Juan¹²,Jiang Chenlong¹,Sun Yangyang¹,Gao Yanni¹,Nauwynck Hans³,Jiang Ping¹²^ORCID,Liu Xing¹²^ORCID

Affiliation:

1. Key Laboratory of Animal Disease Diagnostics and Immunology, Ministry of Agriculture, MOE International Joint Collaborative Research Laboratory for Animal Health & Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, China

2. Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou University, Yangzhou, People’s Republic of China

3. Laboratory of Virology, Faculty of Veterinary Medicine, Ghent University, Merelbeke, Belgium

Abstract

Porcine reproductive and respiratory syndrome virus (PRRSV), a member of the family Arteriviridae , is responsible for reproductive disorders in pregnant sows and respiratory problems in piglets, resulting in huge losses in the swine industry worldwide. Of note, PRRSV infection causes immunosuppression, of which the mechanism is not completely understood.

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/jvi.00188-23

Reference53 articles.

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4. PRRSV structure, replication and recombination: Origin of phenotype and genotype diversity

5. Distinct and Orchestrated Functions of RNA Sensors in Innate Immunity

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