Evaluation of Risk Factors for Coinfection or Cocolonization with Vancomycin-Resistant Enterococcus and Methicillin-Resistant Staphylococcus aureus

Author:

Reyes Katherine1,Malik Rushdah2,Moore Carol1,Donabedian Susan1,Perri Mary1,Johnson Laura1,Zervos Marcus13

Affiliation:

1. Division of Infectious Diseases, Henry Ford Health System, Detroit, Michigan

2. St. Joseph's Mercy Oakland Hospital, Pontiac, Michigan

3. Wayne State University, School of Medicine, Detroit, Michigan

Abstract

ABSTRACT We retrospectively evaluated 410 patients with coinfection or cocolonization due to vancomycin-resistant (VR) enterococcus (VRE) and methicillin-resistant Staphylococcus aureus (MRSA). The prevalence rate was 19.8%. Risk factors included isolation of VR Enterococcus faecalis and use of linezolid or clindamycin. Inc18-like vanA plasmids were found in 7% of VR E. faecalis isolates and none of the VR E. faecium isolates.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Reference17 articles.

1. Benson, L., B. Spraque, J. Campos, and N. Singh. 2007. Epidemiology of infection and colonization with vancomycin-resistant enterococci and frequency of cocolonization with methicillin-resistant Staphylococcus aureus in children. Infect. Control Hosp. Epidemiol. 28 : 880-882.

2. Centers for Disease Control and Prevention. 1995. Recommendations for preventing the spread of vancomycin resistance. Recommendations of the Hospital Infection Control Practices Advisory Committee (HICPAC). MMWR Morb. Mortal. Wkly. Rep. 44 : 1-13.

3. Infection with Vancomycin-ResistantStaphylococcus aureusContaining thevanAResistance Gene

4. Performance standards for antimicrobial susceptibility testing: 15th informational supplement. 2005

5. PlasmidContent of a Vancomycin-Resistant Enterococcus faecalis Isolate from a Patient Also Colonized by Staphylococcusaureus with a VanAPhenotype

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