Palmitoylation at Residue C221 of Japanese Encephalitis Virus NS2A Protein Contributes to Viral Replication Efficiency and Virulence-Reference-Cited by-同舟云学术

Palmitoylation at Residue C221 of Japanese Encephalitis Virus NS2A Protein Contributes to Viral Replication Efficiency and Virulence

Published:2023-06-29 Issue:6 Volume:97 Page:
ISSN:0022-538X
Container-title:Journal of Virology
language:en
Short-container-title:J Virol

Author:

Ma Xiaochun¹²,Xia Qiqi¹,Liu Ke¹,Wu Zhuanchang³,Li Chenxi¹,Xiao Changguang¹,Dong Nihua¹,Hameed Muddassar¹,Anwar Muhammad Naveed¹⁴,Li Zongjie¹,Shao Donghua¹,Li Beibei¹,Qiu Yafeng¹,Wei Jianchao¹^ORCID,Ma Zhiyong¹^ORCID

Affiliation:

1. Shanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Shanghai, People’s Republic of China

2. College of Veterinary Medicine, Shandong Vocational Animal Science and Veterinary College, Weifang, People’s Republic of China

3. Key Laboratory for Experimental Teratology of Ministry of Education and Department of Immunology, School of Basic Medical Science, Shandong University, Jinan, People’s Republic of China

4. Institute of Microbiology, University of Agriculture, Faisalabad, Pakistan

Abstract

An internal cleavage site is present at the C terminus of JEV NS2A. Following occurrence of the internal cleavage, the C-terminal tail (amino acids 195 to 227) is removed from the full-length NS2A.

Funder

MOST | National Key Research and Development Program of China

Shanghai Municipal Science and Technology Major Project

Science and Technology Commission of Shanghai Municipality

MOST | National Natural Science Foundation of China

Central Public-intrest Scientific Institution Basal Research Fund

Natural Science Foundation of Shanghai

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/jvi.00382-23

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