The Stringent Response Inhibits 70S Ribosome Formation in Staphylococcus aureus by Impeding GTPase-Ribosome Interactions-Reference-Cited by-同舟云学术

The Stringent Response Inhibits 70S Ribosome Formation in Staphylococcus aureus by Impeding GTPase-Ribosome Interactions

Published:2021-12-21 Issue:6 Volume:12 Page:
ISSN:2150-7511
Container-title:mBio
language:en
Short-container-title:mBio

Author:

Bennison Daniel J.¹²^ORCID,Nakamoto Jose A.³,Craggs Timothy D.⁴,Milón Pohl³,Rafferty John B.²,Corrigan Rebecca M.¹²^ORCID

Affiliation:

1. The Florey Institute, Department of Molecular Biology and Biotechnology, University of Sheffield, Sheffield, United Kingdom

2. Department of Molecular Biology and Biotechnology, University of Sheffield, Sheffield, United Kingdom

3. Laboratory of Applied Biophysics and Biochemistry, Centre for Research and Innovation, Health Sciences Faculty, Universidad Peruana de Ciencias Aplicadas (UPC), Lima, Peru

4. Sheffield Institute for Nucleic Acids, Department of Chemistry, University of Sheffield, Sheffield, United Kingdom

Abstract

The stringent response is a bacterial signaling network that utilizes the nucleotides pppGpp and ppGpp to reprogram cells in order to survive nutritional stresses. However, much about how these important nucleotides control cellular reprogramming is unknown.

Funder

Wellcome

Lister Institute of Preventive Medicine

UKRI | Medical Research Council

UKRI | Biotechnology and Biological Sciences Research Council

CONCYTEC | Fondo Nacional de Desarrollo Científico, Tecnológico y de Innovación Tecnológica

innovatePeru

Publisher

American Society for Microbiology

Subject

Virology,Microbiology

Link