Clinical Isolates of Enterobacteriaceae Producing Extended-Spectrum β-Lactamases: Prevalence of CTX-M-3 at a Hospital in China-Reference-Cited by-同舟云学术

Clinical Isolates of Enterobacteriaceae Producing Extended-Spectrum β-Lactamases: Prevalence of CTX-M-3 at a Hospital in China

Published:2003-02 Issue:2 Volume:47 Page:790-793
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Wang Hui¹,Kelkar Swathi²,Wu Weiyuan¹,Chen Minjun¹,Quinn John P.²

Affiliation:

1. Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing 100730, China

2. Department of Medicine, University of Illinois, Chicago, Illinois 60612

Abstract

ABSTRACT The prevalence of extended-spectrum β-lactamase-producing strains was demonstrated in 5 of 44 (11.4%) Escherichia coli , 17 of 43 (39.5%) Klebsiella pneumoniae , 3 of 50 (6.0%) Enterobacter cloacae , and 2 of 25 (8.0%) Citrobacter freundii strains at a teaching hospital in China. Nineteen of these 27 strains expressed CTX-M-3 β-lactamase (pI 8.6). A subset of the clinical isolates expressing the CTX-M-3 enzyme, tested by pulsed-field gel electrophoresis, revealed multiple clones. Five isolates expressed a novel enzyme, SHV-43 (pI 8.0), which had two substitutions (Leu113Phe and Thr149Ser) compared with SHV-1.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.47.2.790-793.2003

Reference27 articles.

1. bla CTX-M-2 Is Located in an Unusual Class 1 Integron (In35) Which Includes Orf513

2. Countrywide Spread of CTX-M-3 Extended-Spectrum β-Lactamase-Producing Microorganisms of the Family Enterobacteriaceae in Poland

3. Bauernfeind, A., H. Grimm, and S. Schweighart. 1990. A new plasmidic cefotaximase in a clinical isolate of Escherichia coli. Infection18:294-298.

4. Bauernfeind, A., I. Stemplinger, R. Jungwirth, S. Ernst, and J. M. Casellas. 1996. Sequences of β-lactamases genes encoding CTX-M-1 (MEN-1) and CTX-M-2 and relationship of their amino acid sequences with those of other β-lactamases. Antimicrob. Agents Chemother.40:509-513.

5. CTX-M-5, a Novel Cefotaxime-Hydrolyzing β-Lactamase from an Outbreak of Salmonella typhimurium in Latvia

Cited by 70 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Molecular Screening of Carbapenem-Resistant K. pneumoniae (CRKP) Clinical Isolates for Concomitant Occurrence of Beta-Lactam Genes (CTX-M, TEM, and SHV) in the Kingdom of Bahrain;Journal of Clinical Medicine;2023-12-05

2. Enterobacter cloacae Complex and CTX-M Extended-Spectrum β-Lactamases in Algeria;Microbial Drug Resistance;2021-12-10

3. Phenotypic and Molecular Characterization of Commensal, Community-Acquired and Nosocomial Klebsiella spp.;Microorganisms;2021-11-12

4. Synthesis and Characterization of Some Complexes Derived from Isatin Dye Ligand and Study of their Biological Potency and Anticorrosive Behavior on Aluminum Metal in Acidic Medium;Journal of Inorganic and Organometallic Polymers and Materials;2021-11-09

5. Molecular identification of extended spectrum β-lactamases (ESBLs)-producing strains in clinical specimens from Tiruchirappalli, India;Applied Nanoscience;2021-05-28