The Group B Streptococcal Adhesin BspC Interacts with Host Cytokeratin 19 To Promote Colonization of the Female Reproductive Tract-Reference-Cited by-同舟云学术

The Group B Streptococcal Adhesin BspC Interacts with Host Cytokeratin 19 To Promote Colonization of the Female Reproductive Tract

Published:2022-10-26 Issue:5 Volume:13 Page:
ISSN:2150-7511
Container-title:mBio
language:en
Short-container-title:mBio

Author:

Manzer Haider S.¹^ORCID,Nguyen Dustin T.¹,Park Joo Youn²^ORCID,Park Nogi²,Seo Keun Seok²^ORCID,Thornton Justin A.³,Nobbs Angela H.⁴^ORCID,Doran Kelly S.¹^ORCID

Affiliation:

1. University of Colorado Anschutz Medical Campus, Department of Immunology and Microbiology, Aurora, Colorado, USA

2. Mississippi State University, Department of Comparative Biomedical Sciences, College of Veterinary Medicine, Mississippi State, Mississippi, USA

3. Mississippi State University, Department of Biological Sciences, Mississippi State, Mississippi, USA

4. University of Bristol, Bristol Dental School, Bristol, United Kingdom

Abstract

Group B Streptococcus (GBS) asymptomatically colonizes the female reproductive tract (FRT) of up to one third of women, but GBS carriage can lead to adverse pregnancy outcomes, including premature rupture of membranes, preterm labor, and chorioamnionitis. GBS colonization during pregnancy is also the largest predisposing factor for neonatal GBS disease, including pneumonia, sepsis, and meningitis.

Funder

HHS | NIH | National Institute of Allergy and Infectious Diseases

HHS | NIH | National Institute of Neurological Disorders and Stroke

Publisher

American Society for Microbiology

Subject

Virology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/mbio.01781-22

Reference59 articles.

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5. Pregnancy and Neonatal Outcomes of Group B Streptococcus Infection in Preterm Births

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