Fecal microbiomes of laboratory beagles receiving antiparasitic formulations in an experimental setting

Author:

Ottesen Andrea1ORCID,Kocurek Brandon1ORCID,Deaver Christine1ORCID,Chiesa Oscar1ORCID,Cohen Rachael1ORCID,Reed Elizabeth2ORCID,Commichaux Seth3ORCID,Mammel Mark3ORCID,McDermott Patrick1ORCID,Strain Errol2ORCID,Myers Michael1ORCID

Affiliation:

1. Center for Veterinary Medicine, United States Food and Drug Administration , Laurel, Maryland, USA

2. Center for Food Safety and Applied Nutrition, United States Food and Drug Administration , College Park, Maryland, USA

3. Center for Food Safety and Applied Nutrition, United States Food and Drug Administration , Laurel, Maryland, USA

Abstract

ABSTRACT Here, we describe the fecal microbiome of laboratory beagles in a non-invasive experiment designed to contrast in vivo versus in vitro bioequivalence in response to antiparasitic drug administration. The experiment provided a unique opportunity to evaluate metagenomic profiles of canine feces before and after anti-parasitic drug exposure.

Funder

Center for Veterinary Medicine, FDA

Publisher

American Society for Microbiology

Subject

Genetics,Immunology and Microbiology (miscellaneous),Molecular Biology

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