Antigenic Characterization of Human Monoclonal Antibodies for Therapeutic Use against H7N9 Avian Influenza Virus-Reference-Cited by-全球学者库

Antigenic Characterization of Human Monoclonal Antibodies for Therapeutic Use against H7N9 Avian Influenza Virus

Published:2023-01-31 Issue:1 Volume:97 Page:
ISSN:0022-538X
Container-title:Journal of Virology
language:en
Short-container-title:J Virol

Author:

Chang Pengxiang¹,Lukosaityte Deimante¹,Sealy Joshua E.¹,Rijal Pramila²³,Sadeyen Jean-Remy¹,Bhat Sushant¹^ORCID,Crossley Sylvia¹,Daines Rebecca¹,Huang Kuan-Yin A.⁴⁵,Townsend Alain R.²³,Iqbal Munir¹^ORCID

Affiliation:

1. The Pirbright Institute, Pirbright, Woking, United Kingdom

2. Center for Translational Immunology, Chinese Academy of Medical Science Oxford Institute, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom

3. MRC Human Immunology Unit, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, United Kingdom

4. Graduate Institute of Immunology, College of Medicine, National Taiwan University, Taipei, Taiwan

5. Department of Pediatrics, National Taiwan University Hospital, Taipei, Taiwan

Abstract

Avian influenza virus (AIV) H7N9 continues to circulate and evolve in birds, posing a credible threat to humans. Antiviral drugs have proven useful for the treatment of severe influenza infections in humans; however, concerns have been raised as antiviral-resistant mutants have emerged.

Funder

UKRI | Biotechnology and Biological Sciences Research Council

British Council

Royal Society

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/jvi.01431-22

Reference35 articles.

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2. A hospital cluster combined with a family cluster of avian influenza H7N9 infection in Anhui Province, China

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