Tamm-Horsfall Protein Protects the Urinary Tract against Candida albicans

Author:

Coady Alison1,Ramos Anissa R.1,Olson Joshua1,Nizet Victor12ORCID,Patras Kathryn A.1

Affiliation:

1. Department of Pediatrics, University of California, San Diego, La Jolla, California, USA

2. Skaggs School of Pharmacy & Pharmaceutical Sciences, University of California, San Diego, La Jolla, California, USA

Abstract

Urinary tract infections (UTIs) caused by the human fungal pathogen Candida albicans and related species are prevalent in hospitalized patients, especially those on antibiotic therapy, with indwelling catheters, or with predisposing conditions such as diabetes or immunodeficiency. Understanding of key host defenses against Candida UTI is critical for developing effective treatment strategies.

Funder

HHS | NIH | National Heart, Lung, and Blood Institute

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

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