Genotypic and Phenotypic Diversity among Human Isolates of Akkermansia muciniphila-Reference-Cited by-同舟云学术

Genotypic and Phenotypic Diversity among Human Isolates of Akkermansia muciniphila

Published:2021-05-18 Issue: Volume: Page:
ISSN:2150-7511
Container-title:mBio
language:en
Short-container-title:mBio

Author:

Becken Bradford¹²,Davey Lauren¹,Middleton Dustin R.¹,Mueller Katherine D.¹,Sharma Agastya¹,Holmes Zachary C.¹,Dallow Eric¹,Remick Brenna³,Barton Gregory M.³,David Lawrence A.¹^ORCID,McCann Jessica R.¹,Armstrong Sarah C.²,Malkus Per¹,Valdivia Raphael H.¹^ORCID

Affiliation:

1. Department of Molecular Genetics and Microbiology, Duke University, Durham, North Carolina, USA

2. Department of Pediatrics, Duke University Hospital, Durham, North Carolina, USA

3. Division of Immunology & Pathogenesis, Department of Molecular and Cell Biology, University of California, Berkeley, California, USA

Abstract

The abundance of Akkermansia muciniphila in the gastrointestinal (GI) tract is linked to multiple positive health outcomes. There are four known A. muciniphila phylogroups, yet the prevalence of these phylogroups and how they vary in their ability to influence human health is largely unknown.

Funder

HHS | NIH | National Institute of Allergy and Infectious Diseases

HHS | NIH | National Cancer Institute

HHS | NIH | National Institute of Diabetes and Digestive and Kidney Diseases

American Heart Association

Publisher

American Society for Microbiology

Subject

Virology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/mBio.00478-21

Reference84 articles.