Selection for Phage Resistance Reduces Virulence of Shigella flexneri-Reference-Cited by-同舟云学术

Selection for Phage Resistance Reduces Virulence of Shigella flexneri

Published:2022-01-25 Issue:2 Volume:88 Page:
ISSN:0099-2240
Container-title:Applied and Environmental Microbiology
language:en
Short-container-title:Appl Environ Microbiol

Author:

Kortright Kaitlyn E.¹²,Done Rachel E.²,Chan Benjamin K.²,Souza Valeria³,Turner Paul E.¹²

Affiliation:

1. Program in Microbiology, Yale School of Medicine, New Haven, Connecticut, USA

2. Department of Ecology and Evolutionary Biology, Yale University, New Haven, Connecticut, USA

3. Departamento de Ecologia Evolutiva, Instituto de Ecologia, Universidad Nacional Autonoma de Mexico, Mexico City, Mexico

Abstract

Shigella flexneri is a facultative intracellular pathogen of humans and a leading cause of bacillary dysentery. With few effective treatments and rising antibiotic resistance in these bacteria, there is increasing interest in alternatives to classical infection management of S. flexneri infections.

Funder

Project High Hopes

Publisher

American Society for Microbiology

Subject

Ecology,Applied Microbiology and Biotechnology,Food Science,Biotechnology

Link

https://journals.asm.org/doi/pdf/10.1128/AEM.01514-21

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1. Shigellosis

2. How Do the Virulence Factors of Shigella Work Together to Cause Disease?

3. Recent insights into Shigella