Markedly Increasing Antibiotic Resistance and Dual Treatment of Neisseria gonorrhoeae Isolates in Guangdong, China, from 2013 to 2020

Author:

Lin Xiaomian1ORCID,Qin Xiaolin1,Wu Xingzhong1,Liao Yiwen1,Yu Yuqi12,Xie Qinghui3,Tang Sanmei12,Guo Chixing4,Pei Junming5,Wu Zhizhou6,Cai Changhui7,Wang Feng8,Wu Shanghua9,Chen Heyong10,Liu Xiaofeng11,Li Ming12,Cao Wenling13,Zheng Heping1

Affiliation:

1. Dermatology Hospital, Southern Medical University, Guangzhou, Guangdong, China

2. Guangdong Provincial Center for STD Control, Guangzhou, Guangdong, China

3. Anhui Medical University, Hefei, Anhui, China

4. Guangzhou Panyu Chronic Disease Prevention and Treatment Station, Guangzhou, China

5. Shantou Dermatology Hospital, Shantou, Guangzhou, China

6. Jiangmen Dermatology Hospital, Jiangmen, Guangzhou, China

7. Zhongshan Second People's Hospital, Zhongshan, Guangzhou, China

8. Shenzhen Center for Chronic Diseases Control, Shenzhen, Guangzhou, China

9. Shaoguan Center for Chronic Diseases Control, Shaoguan, Guangzhou, China

10. Maoming Center for Chronic Diseases Control, Maoming, Guangdong, China

11. Zhuhai Center for Chronic Diseases Control, Zhuhai, China

12. Binhai Bay Central Hospital of Dongguan City, Dongguan, China

13. Guangzhou Institute of Dermatology, Guangzhou, China

Abstract

The emergence of multidrug resistance in Neisseria gonorrhoeae is concerning, especially the cooccurrence of azithromycin resistance and decreased susceptibility to extended-spectrum cephalosporin. This study aimed to confirm the antibiotic resistance trends and provide a solution for N. gonorrhoeae treatment in Guangdong, China.

Funder

Health Department of Guangdong Province | Medical Science and Technology Foundation of Guangdong Province

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

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