Transcriptomic Profiling Reveals Intense Host-Pathogen Dispute Compromising Homeostasis during Acute Rift Valley Fever Virus Infection

Author:

Bermúdez-Méndez Erick1234ORCID,Angelino Paolo345ORCID,van Keulen Lucien6,van de Water Sandra1,Rockx Barry1ORCID,Pijlman Gorben P.2ORCID,Ciuffi Angela34ORCID,Kortekaas Jeroen12ORCID,Wichgers Schreur Paul J.1ORCID

Affiliation:

1. Department of Virology and Molecular Biology, Wageningen Bioveterinary Research, Lelystad, The Netherlands

2. Laboratory of Virology, Wageningen University & Research, Wageningen, The Netherlands

3. Institute of Microbiology, Lausanne University Hospital, Lausanne, Switzerland

4. Institute of Microbiology, University of Lausanne, Lausanne, Switzerland

5. Bioinformatics Core Facility, Swiss Institute of Bioinformatics, Lausanne, Switzerland

6. Department of Bacteriology, Host-Pathogen Interaction and Diagnostics Development, Wageningen Bioveterinary Research, Lelystad, The Netherlands

Abstract

Rift Valley fever virus (RVFV) is a mosquito-transmitted pathogen capable of causing severe disease in animals and humans. Outbreaks of RVFV pose a significant threat to public health and can result in substantial economic losses.

Funder

Graduate School of Production Ecology & Resource Conservation

Universidad de Costa Rica

Rob Goldbach Fund

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

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