Characterization of SARS-CoV-2 RNA, Antibodies, and Neutralizing Capacity in Milk Produced by Women with COVID-19

Author:

Pace Ryan M.1ORCID,Williams Janet E.2ORCID,Järvinen Kirsi M.3,Belfort Mandy B.4,Pace Christina D. W.1,Lackey Kimberly A.1,Gogel Alexandra C.1,Nguyen-Contant Phuong5,Kanagaiah Preshetha5,Fitzgerald Theresa5,Ferri Rita3,Young Bridget3,Rosen-Carole Casey3,Diaz Nichole3,Meehan Courtney L.6,Caffé Beatrice6,Sangster Mark Y.5ORCID,Topham David5ORCID,McGuire Mark A.2,Seppo Antti3,McGuire Michelle K.1ORCID

Affiliation:

1. Margaret Ritchie School of Family and Consumer Sciences, University of Idaho, Moscow, Idaho, USA

2. Department of Animal, Veterinary, and Food Sciences, University of Idaho, Moscow, Idaho, USA

3. Department of Pediatrics, Division of Allergy and Immunology, University of Rochester School of Medicine and Dentistry, Rochester, New York, USA

4. Department of Pediatric Newborn Medicine, Brigham and Women’s Hospital and Harvard Medical School, Boston, Massachusetts, USA

5. David H. Smith Center for Vaccine Biology and Immunology, Department of Microbiology and Immunology, University of Rochester Medical Center, Rochester, New York, USA

6. Department of Anthropology, Washington State University, Pullman, Washington, USA

Abstract

Results from prior studies assaying human milk for the presence of SARS-CoV-2, the causative virus of COVID-19, have suggested milk may act as a potential vehicle for mother-to-child transmission. Most previous studies are limited because they followed only a few participants, were cross-sectional, and/or failed to report how milk was collected and/or analyzed.

Funder

Washington State University Health Equity Research Center

University of Idaho Agricultural Experiment Station

HHS | National Institutes of Health

Bill and Melinda Gates Foundation

Publisher

American Society for Microbiology

Subject

Virology,Microbiology

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