Affiliation:
1. Department of Microbiology, Kyungpook National University, School of Medicine, Daegu 700-422
2. Department of Laboratory Medicine, College of Medicine, Chungbuk National University, Cheongju 361-711, Republic of Korea
Abstract
ABSTRACT
Using 58 isolates of
Acinetobacter
species recovered from a university hospital between August 2004 and March 2005, we performed genomic identification by amplified rRNA gene restriction analysis (ARDRA) and investigated the existence of metallo-β-lactamase (MBL) producers and extended-spectrum β-lactamase (ESBL) producers. Genomic species identification of
Acinetobacter
strains using ARDRA showed that 40 strains were genomic species 2 (
Acinetobacter baumannii
), 9 were 13 sensu Tjernberg and Ursing (13TU), 5 were
Acinetobacter
phenon 6/ct 13TU, and 4 were
Acinetobacter
genospecies 3. Among 58 strains, 13 isolates were MBL producers carrying
bla
IMP-1
or
bla
VIM-2
and 13 isolates were ESBL producers carrying
bla
PER-1
. Notably, the MBL producers were mostly 13TU,
Acinetobacter
phenon 6/ct 13TU, and
Acinetobacter
genospecies 3, which showed susceptibility to ciprofloxacin and ampicillin-sulbactam. However, 12 of 13 strains carrying
bla
PER-1
were
A. baumannii
, showing multidrug resistance. The data revealed that the antimicrobial resistance patterns and resistance-harboring genes of
Acinetobacter
species are remarkably distinct according to the genomic species of
Acinetobacter
isolates.
Publisher
American Society for Microbiology
Cited by
54 articles.
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