Comparative Performance of SARS-CoV-2 Detection Assays Using Seven Different Primer-Probe Sets and One Assay Kit

Author:

Nalla Arun K.1,Casto Amanda M.23,Huang Meei-Li W.1,Perchetti Garrett A.1,Sampoleo Reigran1,Shrestha Lasata1,Wei Yulun1,Zhu Haiying1,Jerome Keith R.13,Greninger Alexander L.1

Affiliation:

1. Department of Laboratory Medicine, University of Washington, Seattle, Washington, USA

2. Department of Medicine, University of Washington, Seattle, Washington, USA

3. Vaccine and Infectious Diseases Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA

Abstract

Nearly 400,000 people worldwide are known to have been infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) beginning in December 2019. The virus has now spread to over 168 countries including the United States, where the first cluster of cases was observed in the Seattle metropolitan area in Washington. Given the rapid increase in the number of cases in many localities, the availability of accurate, high-throughput SARS-CoV-2 testing is vital to efforts to manage the current public health crisis.

Funder

HHS | NIH | National Institute of Allergy and Infectious Diseases

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Reference10 articles.

1. World Health Organization. 2020. Novel coronavirus (2019-nCoV) situation report–1. World Health Organization, Geneva, Switzerland.

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4. Early transmission patterns of coronavirus disease 2019 (COVID-19) in travellers from Wuhan to Thailand, January 2020

5. Sun LH Bernstein L. 21 January 2020. First U.S. case of potentially deadly Chinese coronavirus confirmed in Washington State. Washington Post Washington DC. https://www.washingtonpost.com/health/2020/01/21/coronavirus-us-case/.

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