Antimicrobial Resistance Mechanisms, Multilocus Sequence Typing, and NG-STAR Sequence Types of Diverse Neisseria gonorrhoeae Isolates in KwaZulu-Natal, South Africa

Author:

Mitchev Nireshni1ORCID,Singh Ravesh12,Allam Mushal3ORCID,Kwenda Stanford3,Ismail Arshad3ORCID,Garrett Nigel45,Ramsuran Veron1,Niehaus Abraham J.1,Mlisana Koleka P.146

Affiliation:

1. School of Laboratory Medicine and Medical Sciences, University of KwaZulu-Natal, Durban, South Africa

2. National Health Laboratory Service, Durban, South Africa

3. Sequencing Core Facility, National Institute for Communicable Diseases, National Health Laboratory Service, Johannesburg, South Africa

4. Centre for the AIDS Programme of Research in South Africa, Durban, South Africa

5. School of Nursing and Public Health, Discipline of Public Health Medicine, University of KwaZulu-Natal, Durban, South Africa

6. National Health Laboratory Service, Johannesburg, South Africa

Abstract

Antimicrobial resistance (AMR) is a major challenge to managing infectious diseases. Africa has the highest incidence of gonorrhoea, but there is a lack of comprehensive data from sparse surveillance programs.

Funder

National Health Laboratory Service

National Research Foundation

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Reference59 articles.

1. Christodoulides M (ed). 2019. Neisseria gonorrhoeae: methods and protocols. Methods in molecular biology vol 1997. Humana Press Springer US New York NY. 10.1007/978-1-4939-9496-0.

2. Sexually transmitted diseases treatment guidelines, 2015;Workowski KA;MMWR Recomm Rep,2015

3. World Health Organization. 2012. Global action plan to control the spread and impact of antimicrobial resistance in Neisseria gonorrhoeae. https://www.who.int/reproductivehealth/publications/rtis/9789241503501/en/.

4. Screening tests to detect Chlamydia trachomatis and Neisseria gonorrhoeae infections–2002;Johnson RE;MMWR Recomm Rep,2002

5. Chlamydia and Gonorrhea in HIV-Infected Pregnant Women and Infant HIV Transmission

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