Tetracycline Resistance in Group A Streptococci: Emergence on a Global Scale and Influence on Multiple-Drug Resistance

Author:

Ayer Vanessa1,Tewodros Wezenet1,Manoharan Anand1,Skariah Sini1,Luo Feng1,Bessen Debra E.1

Affiliation:

1. Department of Microbiology and Immunology, New York Medical College, Valhalla, New York

Abstract

ABSTRACT A global sample of group A streptococci (GAS) revealed ≥80 separate acquisitions of tetracycline resistance. Of 244 clones, 38 and 25% displayed resistance to tetracycline and erythromycin, respectively; a relatively high proportion (15%) were resistant to both classes of drugs. tet (M) displayed a highly significant association with erm (B).

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

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