Direct Evidence by DNA Fingerprinting that Endoscopic Cross-Infection of Helicobacter pylori Is a Cause of Postendoscopic Acute Gastritis

Author:

Sugiyama Toshiro1,Naka Hiroji1,Yachi Akira2,Asaka Masahiro1

Affiliation:

1. Third Department of Internal Medicine, Hokkaido University School of Medicine,1 and

2. Sapporo Medical University,2 Sapporo, Japan

Abstract

ABSTRACT The DNA fingerprinting of Helicobacter pylori strains in two cases of acute gastritis that occurred after endoscopy was examined. H. pylori was isolated from the stomachs of two patients with acute gastritis and from the stomachs of the patients in whom the same gastrofiberscope had previously been used. The genomic DNA digested with Hae III was subjected to pulsed-field gel electrophoresis. The corresponding paired electrophoretic patterns were completely identical. These findings provide direct evidence that postendoscopic acute gastritis can be caused by cross-infection with H. pylori via endoscopy.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

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