Novel Type of Staphylococcal Cassette Chromosome mec Identified in Community-Acquired Methicillin-Resistant Staphylococcus aureus Strains-Reference-Cited by-同舟云学术

Novel Type of Staphylococcal Cassette Chromosome mec Identified in Community-Acquired Methicillin-Resistant Staphylococcus aureus Strains

Published:2002-04 Issue:4 Volume:46 Page:1147-1152
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Ma Xiao Xue¹,Ito Teruyo¹,Tiensasitorn Chuntima¹,Jamklang Mantana¹,Chongtrakool Piriyaporn¹,Boyle-Vavra Susan²,Daum Robert S.²,Hiramatsu Keiichi¹

Affiliation:

1. Department of Bacteriology, Juntendo University, Tokyo, Japan

2. Department of Pediatrics, University of Chicago Children's Hospital, Chicago, Illinois

Abstract

ABSTRACT We identified a new type of staphylococcal cassette chromosome mec (SCC mec ) from two community-acquired methicillin-resistant Staphylococcus aureus (MRSA) strains. The novel element, designated type IV SCC mec , had a unique combination of the class B mec gene complex and the type 2 ccr gene complex and was much smaller in size (21 to 24 kb) than previously identified SCC mec elements of hospital-acquired MRSA. Consistent with the strains' susceptibilities to various non-β-lactam antibiotics, the type IV SCC mec was devoid of any antibiotic resistance genes other than the mecA gene.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.46.4.1147-1152.2002

Reference23 articles.

1. Basic local alignment search tool

2. Brown, D. F., and P. E. Reynolds. 1980. Intrinsic resistance to beta-lactam antibiotics in Staphylococcus aureus. FEBS Lett.122:275-278.

3. Centers for Disease Control and Prevention. 1999. Four pediatric deaths from community-acquired methicillin-resistant Staphylococcus aureus—Minnesota and North Dakota, 1997-1999. Morb. Mortal. Wkly. Rep.48:707-710.

4. Chambers, H. F. 2001. The changing epidemiology of Staphylococcus aureus. Emerg. Infect. Dis.7:178-182.

5. Embil, J., K. Ramotar, L. Tomance, M. Alfa, J. Conly, S. Cronk, G. Taylor, B. Sutherland, T. Louie, E. Henderson, et al. 1994. Methicillin-resistant Staphylococcus aureus in tertiary care institutions on the Canadian prairies 1990-1992. Infect. Control. Hosp. Epidemiol.15:646-651.

Cited by 486 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Genomic Analysis of a Community-Acquired Methicillin-Resistant Staphylococcus aureus Sequence Type 1 Associated with Caprine Mastitis;Pathogens;2023-12-26

2. Virulence attributes of successful methicillin-resistant Staphylococcus aureus lineages;Clinical Microbiology Reviews;2023-12-20

3. Bacteriophage endolysin Ply113 as a potent antibacterial agent against polymicrobial biofilms formed by enterococci and Staphylococcus aureus;Frontiers in Microbiology;2023-12-12

4. Current types of staphylococcal cassette chromosome mec (SCC mec ) in clinically relevant coagulase-negative staphylococcal (CoNS) species;Critical Reviews in Microbiology;2023-10-26

5. The effect of Staphylococcus aureus on innate and adaptive immunity and potential immunotherapy for S. aureus-induced osteomyelitis;Frontiers in Immunology;2023-09-08