Clostridium difficile Mixed Infection and Reinfection-Reference-Cited by-同舟云学术

Clostridium difficile Mixed Infection and Reinfection

Published:2012-01 Issue:1 Volume:50 Page:142-144
ISSN:0095-1137
Container-title:Journal of Clinical Microbiology
language:en
Short-container-title:J Clin Microbiol

Author:

Eyre David W.¹,Walker A. Sarah¹²,Griffiths David¹,Wilcox Mark H.³⁴,Wyllie David H.¹,Dingle Kate E.¹,Crook Derrick W.¹,Peto Tim E. A.¹

Affiliation:

1. NIHR Oxford Biomedical Research Centre, John Radcliffe Hospital, Oxford, United Kingdom

2. MRC Clinical Trials Unit, London, United Kingdom

3. Department of Microbiology, The General Infirmary, Old Medical School, Leeds, United Kingdom

4. Leeds Institute of Molecular Medicine, University of Leeds, Leeds, United Kingdom

Abstract

ABSTRACTIsolates from consecutiveClostridium difficileinfection (CDI) fecal samples underwent multilocus sequence typing. Potential reinfections with different genotypes were identified in 88/560 (16%) sample pairs taken 1 to 1,414 days (median, 24; interquartile range [IQR], 1 to 52 days) apart; odds of reinfection increased by 58% for every doubling of time between samples. Of 109 sample pairs taken on the same day, 3 (3%) had different genotypes. Considering samples 0 to 7 days apart as the same CDI, 7% of cases had mixed infections with >1 genotype.

Publisher

American Society for Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/JCM.05177-11

Reference12 articles.

1. Epidemiology of Recurrences or Reinfections of Clostridium difficile -Associated Diarrhea

2. Defining criteria to interpret multilocus variable-number tandem repeat analysis to aid Clostridium difficile outbreak investigation

3. Clinical Clostridium difficile: Clonality and Pathogenicity Locus Diversity

4. Multilocus Sequence Typing of Clostridium difficile

5. Recurrences of Clostridium difficile Diarrhea Not Caused by the Original Infecting Organism

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