Ferric Citrate Uptake Is a Virulence Factor in Uropathogenic Escherichia coli

Author:

Frick-Cheng Arwen E.1ORCID,Sintsova Anna1,Smith Sara N.1,Pirani Ali1,Snitkin Evan S.1ORCID,Mobley Harry L. T.1ORCID

Affiliation:

1. Department of Microbiology and Immunology, University of Michigan, Ann Arbor, Michigan, USA

Abstract

UPEC, the primary causative agent of uncomplicated UTI, is responsible for five billion dollars in health care costs in the United States each year. Rates of antibiotic resistance are on the rise; therefore, it is vital to understand the mechanisms of UPEC pathogenesis to uncover potential targets for novel therapeutics.

Funder

HHS | NIH | National Institute of Diabetes and Digestive and Kidney Diseases

Publisher

American Society for Microbiology

Subject

Virology,Microbiology

Reference61 articles.

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