Effect of iron-limiting conditions on growth of clinical isolates of Acinetobacter baumannii

Author:

Actis L A1,Tolmasky M E1,Crosa L M1,Crosa J H1

Affiliation:

1. Department of Microbiology and Immunology, School of Medicine, Oregon Health Sciences University, Portland 97201-3098.

Abstract

Different clinical isolates of Acinetobacter baumannii, typed by plasmid profile, were able to grow in iron-chelated medium by secreting iron-regulated siderophores. This iron-scavenging phenotype was associated with the production of iron-repressible catechol. Siderophore utilization bioassays showed the presence of 2,3-dihydroxybenzoic acid in the growth medium, and neither enterobactin nor aerobactin was detected in culture supernatants obtained under iron-deficient conditions.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

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