The Human Virome: Implications for Clinical Practice in Transplantation Medicine-Reference-Cited by-同舟云学术

The Human Virome: Implications for Clinical Practice in Transplantation Medicine

Published:2017-10 Issue:10 Volume:55 Page:2884-2893
ISSN:0095-1137
Container-title:Journal of Clinical Microbiology
language:en
Short-container-title:J Clin Microbiol

Author:

Tan Susanna K.¹,Relman David A.¹²³,Pinsky Benjamin A.¹⁴^ORCID

Affiliation:

1. Department of Medicine, Division of Infectious Diseases and Geographic Medicine, Stanford University School of Medicine, Stanford, California, USA

2. Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, California, USA

3. Veterans Affairs Palo Alto Health Care System, Palo Alto, California, USA

4. Department of Pathology, Stanford University School of Medicine, Stanford, California, USA

Abstract

ABSTRACT Advances in DNA sequencing technology have provided an unprecedented opportunity to study the human virome. Transplant recipients and other immunocompromised hosts are at particular risk for developing virus-related pathology; thus, the impact of the virome on health and disease may be even more relevant in this population. Here, we discuss technical considerations in studying the human virome, the current literature on the virome in transplant recipients, and near-future applications of sequence-based findings that can further our understanding of viruses in transplantation medicine.

Funder

Thomas C. and Joan M. Merigan Endowment at Stanford University

HHS | NIH | National Institute of Allergy and Infectious Diseases

HHS | NIH | National Center for Advancing Translational Sciences

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Link

https://journals.asm.org/doi/pdf/10.1128/JCM.00489-17

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1. Beyond the gut bacterial microbiota: The gut virome