Affiliation:
1. Institute for Genomic Biology, University of Illinois, Urbana, Illinois 61801
Abstract
ABSTRACT
Carboxylases are among the most important enzymes in the biosphere, because they catalyze a key reaction in the global carbon cycle: the fixation of inorganic carbon (CO
2
). This minireview discusses the physiological roles of carboxylases in different microbial pathways that range from autotrophy, carbon assimilation, and anaplerosis to biosynthetic and redox-balancing functions. In addition, the current and possible future uses of carboxylation reactions in synthetic biology are discussed. Such uses include the possible transformation of the greenhouse gas carbon dioxide into value-added compounds and the production of novel antibiotics.
Publisher
American Society for Microbiology
Subject
Ecology,Applied Microbiology and Biotechnology,Food Science,Biotechnology
Reference136 articles.
1. Identification of enzymes involved in anaerobic benzene degradation by a strictly anaerobic iron-reducing enrichment culture;Abu Laban N.;Environ. Microbiol,2010
2. Oxidoreductase-Type Enzymes and Redox Proteins Involved in Fermentative Metabolisms of Hyperthermophilic Archaea
3. Advanced Research Projects Agency. 5 May 2011 accession date. ARPA-E electrofuels project summary. U.S. Department of Energy Washington DC. http://arpa-e.energy.gov/LinkClick.aspx?fileticket=TRv8LDEgnhw%3D&tabid=82.
4. Substrate Specificity of the 3-Methylcrotonyl Coenzyme A (CoA) and Geranyl-CoA Carboxylases from
Pseudomonas aeruginosa
5. AnthonyC. 1982. Methylotrophic bacteria, p. 1–40. In The biochemistry of methylotrophs. Academic Press, London, United Kingdom.
Cited by
154 articles.
订阅此论文施引文献
订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献