Organization of the Skin Immune System and Compartmentalized Immune Responses in Infectious Diseases

Author:

Quaresma Juarez Antonio Simões1234ORCID

Affiliation:

1. Center of Biological and Health Sciences, State University of Pará, Belém, PA, Brazil

2. Evandro Chagas Institute, Ministry of Health, Ananindeua, PA, Brazil

3. Tropical Medicine Center, Federal University of Pará, Belém, PA, Brazil

4. School of Medicine, São Paulo University, São Paulo, SP, Brazil

Abstract

The skin is an organ harboring several types of immune cells that participate in innate and adaptive immune responses. The immune system of the skin comprises both skin cells and professional immune cells that together constitute what is designated skin-associated lymphoid tissue (SALT). In this review, I extensively discuss the organization of SALT and the mechanisms involved in its responses to infectious diseases of the skin and mucosa.

Funder

MCTI | Conselho Nacional de Desenvolvimento Científico e Tecnológico

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Microbiology (medical),Public Health, Environmental and Occupational Health,General Immunology and Microbiology,Epidemiology

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