TRAF6 and TAK1 Contribute to SAMHD1-Mediated Negative Regulation of NF-κB Signaling
Author:
Affiliation:
1. Department of Microbiology and Immunology, Carver College of Medicine, The University of Iowa, Iowa City, Iowa, USA
2. Center for Retrovirus Research, Department of Veterinary Biosciences, The Ohio State University, Columbus, Ohio, USA
Abstract
Funder
HHS | NIH | National Institute of Allergy and Infectious Diseases
Publisher
American Society for Microbiology
Subject
Virology,Insect Science,Immunology,Microbiology
Link
https://journals.asm.org/doi/pdf/10.1128/JVI.01970-20
Reference60 articles.
1. SAMHD1 is the dendritic- and myeloid-cell-specific HIV-1 restriction factor counteracted by Vpx
2. Vpx relieves inhibition of HIV-1 infection of macrophages mediated by the SAMHD1 protein
3. SAMHD1 restricts HIV-1 reverse transcription in quiescent CD4+T-cells
4. SAMHD1 restricts HIV-1 infection in resting CD4+ T cells
5. HIV-1 restriction factor SAMHD1 is a deoxynucleoside triphosphate triphosphohydrolase
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