Plasmid-Mediated Quinolone Resistance in Extended-Spectrum-β-Lactamase- and AmpC β-Lactamase-Producing Serratia marcescens in China

Author:

Yang Hai-Fei,Cheng Jun,Hu Li-Fen,Ye Ying,Li Jia-Bin

Abstract

ABSTRACTWe investigated the prevalence of plasmid-mediated quinolone resistance (PMQR) determinants and examined the association of these determinants with extended-spectrum β-lactamases (ESBLs) and/or plasmid-mediated AmpC β-lactamases (pAmpCs) inSerratia marcescensisolates in China. In this study, the presence of PMQR determinants was significantly related to the coproduction of ESBLs and/or pAmpCs (CTX-M-14, SHV-5, DHA-1, and ACT-1), among which CTX-M-14 was the most common gene type.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

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