Tolerance of Benznidazole in Treatment of Chagas' Disease in Adults-Reference-Cited by-同舟云学术

Tolerance of Benznidazole in Treatment of Chagas' Disease in Adults

Published:2010-11 Issue:11 Volume:54 Page:4896-4899
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Pinazo María-Jesús¹,Muñoz José¹,Posada Elizabeth¹,López-Chejade Paulo²,Gállego Montserrat²,Ayala Edgar³,del Cacho Elena⁴,Soy Dolors⁴,Gascon Joaquim¹

Affiliation:

1. Tropical Diseases Section, Barcelona Center for International Health Research (CRESIB), Hospital Clinic, Villarroel 170, 08036 Barcelona, Spain

2. Laboratori de Parasitologia, Facultat de Farmàcia, Universitat de Barcelona, Joan XXIII Avenue, s/n 08028 Barcelona, Spain

3. Center for International Health Research (CRESIB), Roselló 132, 08036 Barcelona, Spain

4. Pharmacology Department, Hospital Clinic, Villarroel 170, 08036 Barcelona, Spain

Abstract

ABSTRACT Chagas’ disease is an emerging public health problem in areas where the disease is not endemic. Treatment with benznidazole has shown efficacy in the acute stage of the disease, but its efficacy in the chronic stage remains controversial, and unwanted side effects are more frequent and severe in adults than in children. This study describes the profile of side effects of benznidazole in a cohort of Trypanosoma cruzi -infected patients in a European country.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.00537-10

Reference25 articles.

1. Cançado, J. R. 2002. Long term evaluation of etiological treatment of Chagas’ disease with benznidazole. Rev. Inst. Med. Trop. Sao Paulo44:29-37.

2. Carpintero, D. J. 1983. Uso del ácido tióctico para la prevención de los efectos secundarios provocados por el benznidazol en pacientes con enfermedad de Chagas crónica. Medicina (B. Aires).43:285-290.

3. Coura, R. J., and S. L. de Castro. 2002. A critical review on Chagas’ disease chemotherapy. Mem. Inst. Oswaldo Cruz97:3-24.

4. Randomised trial of efficacy of benznidazole in treatment of early Trypanosoma cruzi infection

5. Fabbro, D. L., M. L. Streiger, E. D. Arias, M. L. Bizai, M. del Barco, and N. A. Amicone. 2007. Trypanocide treatment among adults with chronic Chagas’ disease living in Santa Fe city (Argentina), over a mean follow-up of 21 years: parasitological, serological and clinical evolution. Rev. Soc. Bras. Med. Trop.40:1-10.

Cited by 150 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Chagas disease in immunocompromised patients;Clinical Microbiology Reviews;2024-06-13

2. Immunoglobulin and T cell receptor repertoire changes induced by a prototype vaccine against Chagas disease in naïve rhesus macaques;Journal of Biomedical Science;2024-06-01

3. Benznidazole-induced drug reaction with eosinophilia and systemic symptoms syndrome in a patient with human leucocyte antigen (HLA)-A*68;European Journal of Hospital Pharmacy;2024-01-18

4. Machine Learning-Based Approach to Identify Inhibitors of Sterol-14-Alpha Demethylase: A Study on Chagas Disease;Bioinformatics and Biology Insights;2024-01

5. The impact of vaccine-linked chemotherapy on liver health in a mouse model of chronic Trypanosoma cruzi infection;PLOS Neglected Tropical Diseases;2023-11-21