Antiviral Approaches against Influenza Virus

Author:

Kumari Rashmi12,Sharma Suresh D.1,Kumar Amrita1,Ende Zachary13,Mishina Margarita1,Wang Yuanyuan45,Falls Zackary6,Samudrala Ram6,Pohl Jan4,Knight Paul R.2,Sambhara Suryaprakash1ORCID

Affiliation:

1. Immunology and Pathogenesis Branch, Influenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA

2. Department of Anesthesiology, Jacobs School of Medicine and Biomedical Sciences, State University of New York at Buffalo, Buffalo, New York, USA

3. Oak Ridge Institute for Science and Education (ORISE), CDC Fellowship Program, Oak Ridge, Tennessee, USA

4. Biotechnology Core Facility Branch, Division of Scientific Resources, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA

5. Association of Public Health Laboratories, Silver Spring, Maryland, USA

6. Department of Biomedical Informatics, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, New York, USA

Abstract

Preventing and controlling influenza virus infection remains a global public health challenge, as it causes seasonal epidemics to unexpected pandemics. These infections are responsible for high morbidity, mortality, and substantial economic impact.

Funder

HHS | NIH | National Heart, Lung, and Blood Institute

HHS | National Institutes of Health

HHS | NIH | U.S. National Library of Medicine

HHS | NIH | National Center for Advancing Translational Sciences

National Institute of Development Administration

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Microbiology (medical),Public Health, Environmental and Occupational Health,General Immunology and Microbiology,Epidemiology

Reference423 articles.

1. World Health Organization. 2022. Comparison of number of influenza detections by subtype. https://app.powerbi.com/view?r=eyJrIjoiZTIxMzAwMzYtZWE4NC00YTU2LWE3MTUtMTI0OGY1ZjQyMWViIiwidCI6ImY2MTBjMGI3LWJkMjQtNGIzOS04MTBiLTNkYzI4MGFmYjU5MCIsImMiOjh9. Retrieved 18 February 2022.

2. Centers for Disease Control and Prevention. 2022. Weekly U.S. influenza surveillance report. https://www.cdc.gov/flu/weekly/index.htm. Retrieved 18 February 2022.

3. Estimates of global seasonal influenza-associated respiratory mortality: a modelling study

4. Centers for Disease Control and Prevention. 2020. Past seasons estimated influenza disease burden. https://www.cdc.gov/flu/about/burden/past-seasons.html?web=1&wdLOR=cEAB96504-2317-493E-BEF7-B9E799A85D55. Retrieved 18 February 2022.

5. Centers for Disease Control and Prevention. 2021. People at higher risk of flu complications https://www.cdc.gov/flu/highrisk/index.htm. Retrieved 18 February 2022.

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