9-Butyl-Harmol Exerts Antiviral Activity against Newcastle Disease Virus through Targeting GSK-3β and HSP90β

Author:

Wang Chongyang12,Wang Ting1,Hu Ruochen1,Duan Liuyuan1,Hou Qili1,Han Yu1,Dai Jiangkun2,Wang Wenbin3,Ren Shanhui4,Liu Haijin1,Wang Xinglong1ORCID,Xiao Sa1,Li Na5,Wang Junru2,Yang Zengqi1ORCID

Affiliation:

1. College of Veterinary Medicine, Northwest A&F University, Yangling, China

2. College of Chemistry and Pharmacy, Northwest A&F University, Yangling, China

3. Poultry Institute, Shandong Academy of Agricultural Science, Jinan, China

4. State Key Laboratory of Veterinary Etiological Biology, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, China

5. Instrumental Analysis Center, Xi'an Jiaotong University, Xi’an, China

Abstract

Paramyxoviruses cause devastating impacts on health and the economy worldwide. However, there are no suitable drugs with which to counteract the viruses.

Funder

China Postdoctoral Science Foundation

National Natural Science Foundation of China

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

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