Meropenem-Vaborbactam versus Ceftazidime-Avibactam for Treatment of Carbapenem-Resistant Enterobacteriaceae Infections-Reference-Cited by-同舟云学术

Meropenem-Vaborbactam versus Ceftazidime-Avibactam for Treatment of Carbapenem-Resistant Enterobacteriaceae Infections

Published:2020-04-21 Issue:5 Volume:64 Page:
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Ackley Renee¹,Roshdy Danya¹,Meredith Jacqueline¹,Minor Sarah²,Anderson William E.³,Capraro Gerald A.⁴,Polk Christopher⁵

Affiliation:

1. Department of Pharmacy, Atrium Health, Charlotte, North Carolina, USA

2. Department of Pharmacy, AdventHealth, Orlando, Florida, USA

3. Center for Outcomes Research and Evaluation, Charlotte, North Carolina, USA

4. Carolinas Pathology, Atrium Health Clinical Microbiology Laboratory, Charlotte, North Carolina, USA

5. Department of Internal Medicine, Division of Infectious Diseases, Atrium Health, Charlotte, North Carolina, USA

Abstract

The comparative efficacy of ceftazidime-avibactam and meropenem-vaborbactam for treatment of carbapenem-resistant Enterobacteriaceae (CRE) infections remains unknown. This was a multicenter, retrospective cohort study of adults with CRE infections who received ceftazidime-avibactam or meropenem-vaborbactam for ≥72 hours from February 2015 to October 2018. Patients with a localized urinary tract infection and repeat study drug exposures after the first episode were excluded.

Funder

Melinta Therapeutics, Inc.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.02313-19

Reference29 articles.

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