Real-Time Analysis of Mucosal Flora in Patients with Inflammatory Bowel Disease in India

Author:

Verma Ravi1,Verma Anil Kumar1,Ahuja Vineet2,Paul Jaishree1

Affiliation:

1. School of Life Sciences, Jawaharlal Nehru University, New Delhi, India

2. Department of Gastroenterology, All India Institute of Medical Sciences, New Delhi, India

Abstract

ABSTRACT Mucosa-associated bacterial flora from control individuals and inflammatory bowel disease (IBD) patients were evaluated by real-time analysis using 16S rRNA-based genus-specific primers. Our data show a clear delineation in concentration of bacteria between the predominating and subdominating genera under disease conditions, indicating that the subsets of bacteria participating in the pathogenesis of ulcerative colitis (UC) and Crohn's disease (CD) are likely to be different.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

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