Phenotypic and Genomic Comparison of Staphylococcus aureus Highlight Virulence and Host Adaptation Favoring the Success of Epidemic Clones

Author:

Chen Fengning12,Yin Yuyao2,Chen Hongbin2ORCID,Jin Longyang2,Li Shuguang2,Wang Ruobing2,Wang Shuyi1,Wang Qi2,Sun Shijun2,Wang Hui12ORCID

Affiliation:

1. Institute of Medical Technology, Peking University Health Science Center, Beijing, China

2. Department of Clinical Laboratory, Peking University People’s Hospital, Beijing, China

Abstract

Considerable efforts have been exerted to identify factors contributing to the success of epidemic Staphylococcus aureus clones, however, comparative phenotypic studies lack representation owing to the small number of strains. Large-scale strain collections focused on the description of genomic characteristics.

Funder

National Natural Science Foundation of China

Publisher

American Society for Microbiology

Subject

Computer Science Applications,Genetics,Molecular Biology,Modeling and Simulation,Ecology, Evolution, Behavior and Systematics,Biochemistry,Physiology,Microbiology

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