Leishmania donovani Impedes Antileishmanial Immunity by Suppressing Dendritic Cells via the TIM-3 Receptor-Reference-Cited by-同舟云学术

Leishmania donovani Impedes Antileishmanial Immunity by Suppressing Dendritic Cells via the TIM-3 Receptor

Published:2022-08-30 Issue:4 Volume:13 Page:
ISSN:2150-7511
Container-title:mBio
language:en
Short-container-title:mBio

Author:

Akhtar Md. Naushad¹,Kumar Sahil¹,Sen Pradip¹^ORCID

Affiliation:

1. Division of Cell Biology and Immunology, Council of Scientific and Industrial Research-Institute of Microbial Technology, Chandigarh, India

Abstract

Visceral leishmaniasis (VL), a poverty-related disease caused by Leishmania donovani , is ranked by the World Health Organization as the second largest killer parasitic disease in the world. The protective immune response against VL is primarily regulated by dendritic cells (DCs), which upon activation/maturation initiate an antileishmanial immune response.

Funder

DST | Science and Engineering Research Board

Council of Scientific and Industrial Research, India

Global Challenges Research Fund

Publisher

American Society for Microbiology

Subject

Virology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/mbio.03309-21

Reference70 articles.

1. Social and Economic Burden of Human Leishmaniasis